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Herpes Simplex Virus, Adenovirus, Poxvirus, Lentivirus, Retrovirus


With more than 10 years of devotion to the field of oncolytic viruses, Binhui Bio has accumulated a wealth of experience in viral vector construction, viral and cell bank establishment, process development, lab and pilot scale production, quality control, and IND application in China and the United States, etc., and has developed a mature service platform for virus vector technology that can provide R&D and production for herpes simplex virus, adenovirus, poxvirus, lentivirus, retrovirus, and other virus vectors.



Bank Establishment for Cells/Viral Strains

Internal Checking of Cell/Viral Strain Bank

Analysis Method Development

Analysis Method Verification

Culture Process Development

Bioreactor Process Development

Virus Purification Process Development

Formulation Process Development

Clinical Batch of Production

Sample Stability Study

IND Document Writing





With a complete set of equipments, a flexible production process, multiple GMP compliant workshops available, it can satisfy with the requirements of virus production for pre-clinical and clinical trial studies.

Three-level bank establishment for virus seed bank and cell bank in GMP compliant workshop, suspended or adherent cell culture, 3L-50L-100L scale-up production.

Disposable and aseptic production process, A-level aseptic isolator filling system, personnel and materials are separated to minimize contamination risk.

Integrated QC system, strict monitoring of the production process, product release, and complete and traceable CMC original records.

High yield, less impurity residue, and low production and purification cost.

Rich experience in different scale of production and IND application. Several viral vector drugs were successfully approved for Sino-US clinical trial application.

Viral Vector Service Manual